PDF(Pubmed)
Abstract：
We report the clinical case of a patient with coronavirus disease 2019 (COVID-19) who had recently undergone neurosurgery and presented with dilated nonreactive pupils during continuous rocuronium infusion, which was reversible with the suspension of the drug. Both the neurosurgical procedure and possible disruption of the blood-brain barrier due to COVID-19 infection may have led to the action of rocuronium in the central nervous system (CNS). Thus, clinicians must remember that neuromuscular blocking agents (NMBAs) can cause dilated nonreactive pupils in patients with COVID-19.
摘要：
我们报告了一名2019年冠状病毒病（COVID-19）患者的临床病例，该患者最近接受了神经外科手术，并在连续输注罗库溴铵期间出现了扩张的非反应性瞳孔，这与药物的悬浮液是可逆的。神经外科手术和COVID-19感染可能导致的血脑屏障破坏都可能导致罗库溴铵在中枢神经系统（CNS）中的作用。因此，临床医生必须记住，神经肌肉阻滞剂（NMBA）可导致COVID-19患者瞳孔扩张，非反应性。
