关键词: Case report Chronic retinal necrosis Cytomegalovirus corneal endotheliitis Polymerase chain reaction Tube shunt surgery

Mesh : Aged, 80 and over Antiviral Agents / therapeutic use Aqueous Humor Cytomegalovirus / genetics Cytomegalovirus Infections / complications drug therapy DNA, Viral Endothelium, Corneal Eye Infections, Viral / diagnosis drug therapy Ganciclovir / therapeutic use Glaucoma / drug therapy surgery Humans Male Necrosis / drug therapy

来  源:   DOI:10.1186/s12886-021-02019-w   PDF(Sci-hub)   PDF(Pubmed)

Abstract:
BACKGROUND: We report a case of chronic retinal necrosis (CRN) combined with cytomegalovirus (CMV) corneal endotheliitis.
METHODS: An 80-year old man was diagnosed with CRN that developed after tube shunt surgery with vitrectomy for secondary glaucoma associated with CMV corneal endotheliitis. After the use of oral valganciclovir and panretinal photocoagulation, the retinal lesion resolved rapidly and he has maintained visual acuity better than before the onset of CRN.
CONCLUSIONS: Use of oral valganciclovir, prophylactic panretinal photocoagulation for the non- perfusion area and vitrectomy were effective in maintaining the visual acuity for the patient with CRN.
摘要:
背景:我们报道了一例慢性视网膜坏死(CRN)合并巨细胞病毒(CMV)角膜内皮炎的病例。
方法:一名80岁的男性被诊断为CRN,该CRN是在行玻璃体切割术治疗与CMV角膜内皮炎相关的继发性青光眼后进行的。口服伐更昔洛韦和全视网膜光凝后,视网膜病变迅速消退,他的视力比CRN发作前更好。
结论:使用口服伐更昔洛韦,非灌注区预防性全视网膜光凝和玻璃体切除术可有效维持CRN患者的视力.
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