关键词: Absidia corymbifera Fungal orbital cellulitis Lichtheimia corymbifera

Mesh : Humans Male Young Adult Adult Retrospective Studies Mycoses

来  源:   DOI:10.1080/09273948.2021.1909735   PDF(Sci-hub)

Abstract:
UNASSIGNED: To present a case of orbital fungal infection caused by a rare fungus, Lichtheimia corymbifera (Absidia corymbifera) in an immunocompetent individual.
UNASSIGNED: A retrospective case study.
UNASSIGNED: A 23-year-old male presented with painful proptosis of the right eye for 3 months. Examination revealed normal vision and pupillary light reflex but restricted ocular movements in the right eye. A tender, firm mass was palpable along the inferomedial quadrant of the right orbit. He had acute worsening of proptosis with loss of light perception within 24 hours. Magnetic resonance imaging (MRI) showed a heterogeneously enhancing lesion in the right orbit. Urgent incisional biopsy revealed the growth of Absidial fungal infection. He received intravenous Amphotericin B for 2 weeks with no response. Repeat MRI revealed an extension of the infection up to the cavernous sinus and intracranial optic nerve. He was managed by subtotal exenteration, socket irrigation with Amphotericin B, and intravenous Amphotericin B.
UNASSIGNED: Invasive orbital fungal infection, though rare, should be considered a differential diagnosis in immunocompetent patients with fulminant proptosis and vision loss.
摘要:
未经证实:介绍一例罕见真菌引起的眼眶真菌感染,具有免疫能力的个体中的Lichtheimiacorymbifera(Absidiacorymbifera)。
未经评估:回顾性案例研究。
未经证实:一名23岁男性右眼眼球突出疼痛3个月。检查显示视力和瞳孔光反射正常,但右眼的眼球运动受限。一个招标,沿着右轨道的下象限可以看到坚固的质量。他在24小时内出现了眼球突出的急性恶化,并失去了光线知觉。磁共振成像(MRI)显示右眼眶有不均匀增强的病变。紧急切开活检显示腹部真菌感染的生长。他接受两性霉素B静脉注射2周,无反应。重复MRI显示感染延伸至海绵窦和颅内视神经。他是通过小计放血来管理的,用两性霉素B进行插座冲洗,和静脉注射两性霉素B。
未经证实:侵袭性眼眶真菌感染,虽然罕见,对于患有暴发性眼球突出和视力丧失的免疫功能正常的患者,应考虑进行鉴别诊断。
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