PDF(Pubmed)
Abstract：
Yellow fever (YF) is a viral haemorrhagic fever caused by yellow fever virus transmitted by Aedes mosquitoes. Since 2013, in Chad, four cases of yellow fever have been detected and confirmed as part of the national fever surveillance program. We here report the last clinical case confirmed in the health district of Lai. The patient was a 57-year-old man with no significant medical and surgical history and unknown immunisation status. He consulted on April 21st, 2020 for fever, moderate to low abundance jaundice and epistaxis (nosebleed) and painful hepatomegaly. Paraclinical examinations, such as RT-PCR, objectified yellow fever virus in post-mortem tissue sample. Thus, confirmed yellow fever cases in this district, the low level of vaccination coverage, the circulation of the virus and the presence of vector in the country should warn of a real threat of reemergence of yellow fever in Chad.
摘要：
黄热病（YF）是由伊蚊传播的黄热病病毒引起的病毒性出血热。自2013年以来，在乍得，作为国家发烧监测计划的一部分，已经发现并确认了四例黄热病。我们在此报告在赖卫生区确认的最后一例临床病例。该患者是一名57岁的男性，没有明显的医疗和手术史，免疫状态未知。他在4月21日咨询过,2020年发烧，中度至低丰度黄疸和鼻出血（鼻出血）和疼痛性肝肿大。临床旁检查，如RT-PCR，尸检组织样本中的黄热病病毒。因此，本区确诊黄热病例,疫苗接种覆盖率低，病毒的传播和病媒在该国的存在应该警告说，黄热病在乍得再次出现的真正威胁。
