Abstract：
In this review, we discuss the role of adrenoceptors in the regulation of the rheological functions of erythrocytes. β-adrenoceptors play an important role in the regulation of erythrocytes functions and metabolism. They participate in the modification of transport membrane proteins (Na+/K+-ATPase, Ca+2-ATPase, Na+/K+/2Cl-cotransporter, Na+/H+-antiporter, CAT-1, Ca2+-dependent K+ channels (Gard channels), the activity of adenylate cyclase and cAMP, AMP-dependent activation of the L-arginine/NOS system and erythrocyte NOS) and by this way modulate the cells volume, rheological properties (deformability, aggregability), intensity of NO synthesis and ATP reliase. These properties of erythrocytes determine, that, in addition to the transport of gases, they play the oxygen sensors role and can participate in the mechanisms of vasorelaxation and maintenance of a normal level of microcirculation.
摘要：
在这次审查中,我们讨论了肾上腺素受体在调节红细胞流变功能中的作用。β-肾上腺素受体在调节红细胞功能和代谢中起重要作用。它们参与转运膜蛋白（Na+/K+-ATP酶，Ca+2-ATP酶,Na+/K+/2Cl-协同转运蛋白,Na+/H+-反转运蛋白,CAT-1，Ca2依赖性K+通道（Gard通道），腺苷酸环化酶和cAMP的活性，L-精氨酸/NOS系统和红细胞NOS的AMP依赖性激活），并通过这种方式调节细胞体积，流变特性(可变形性，可聚合性)，NO合成强度和ATPreliase。红细胞的这些特性决定了,That,除了气体的运输，它们发挥氧传感器的作用，可以参与血管舒张和维持微循环正常水平的机制。
