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Abstract：
UNASSIGNED: The presence of endolymphatic hydrops (ELH) in patients with Meniere\'s disease (MD) is considered a pathological hallmark.
UNASSIGNED: We aimed to conduct a quantitative volumetric measurement of inner ear ELH in patients with unilateral MD (uMD). The values of uMD with and without herniation into the posterior semi-circular canal (h-PSC) and the lateral semi-circular canal (h-LSC) were compared using 3 D magnetic resonance imaging.
UNASSIGNED: This study included 130 individuals (47 controls and 83 patients with uMD). We measured the total fluid space (TFS) and endolymphatic space (ELS) volumes. We also evaluated the ELS/TFS volume ratios (%).
UNASSIGNED: The ELS/TFS volume ratios in the inner ear, cochlea, and vestibule were significantly different between the affected and contralateral sides in patients with h-PSC. Moreover, the ELS/TFS volume ratios of the inner ear, vestibule, and semi-circular canals in the affected ear were significantly higher in patients with h-PSC than in those without h-PSC. The vestibular ELS/TFS volume ratio in the affected ear was significantly higher in patients with h-LSC than in those without h-LSC.
UNASSIGNED: H-LSC is present in extended vestibular ELH. However, this is a result of ELH progression in the inner ear.
UNASSIGNED: We aimed to conduct a quantitative volumetric measurement of inner ear ELH in patients with unilateral MD (uMD). The values of uMD with and without herniation into the posterior semi-circular canal (h-PSC) and the lateral semi-circular canal (h-LSC) were compared using 3 D magnetic resonance imaging.
UNASSIGNED: This study included 130 individuals (47 controls and 83 patients with uMD). We measured the total fluid space (TFS) and endolymphatic space (ELS) volumes. We also evaluated the ELS/TFS volume ratios (%).
UNASSIGNED: The ELS/TFS volume ratios in the inner ear, cochlea, and vestibule were significantly different between the affected and contralateral sides in patients with h-PSC. Moreover, the ELS/TFS volume ratios of the inner ear, vestibule, and semi-circular canals in the affected ear were significantly higher in patients with h-PSC than in those without h-PSC. The vestibular ELS/TFS volume ratio in the affected ear was significantly higher in patients with h-LSC than in those without h-LSC.
UNASSIGNED: H-LSC is present in extended vestibular ELH. However, this is a result of ELH progression in the inner ear.
摘要：
■梅尼埃病（MD）患者中存在内淋巴积水（ELH）被认为是病理标志。
■我们旨在对单侧MD（uMD）患者的内耳ELH进行定量体积测量。使用3D磁共振成像比较了有和没有突出到后半圆形管（h-PSC）和外侧半圆形管（h-LSC）的uMD值。
■该研究包括130名个体(47名对照和83名uMD患者)。我们测量了总流体空间(TFS)和内淋巴空间(ELS)体积。我们还评估了ELS/TFS体积比(%)。
■内耳的ELS/TFS体积比，耳蜗,h-PSC患者患侧和对侧的前庭和前庭之间存在显着差异。此外，内耳的ELS/TFS体积比，前庭,h-PSC患者患耳的半圆形管明显高于无h-PSC患者。h-LSC患者患耳的前庭ELS/TFS体积比明显高于无h-LSC患者。
■H-LSC存在于扩展的前庭ELH中。然而,这是内耳ELH进展的结果。
■我们旨在对单侧MD（uMD）患者的内耳ELH进行定量体积测量。使用3D磁共振成像比较了有和没有突出到后半圆形管（h-PSC）和外侧半圆形管（h-LSC）的uMD值。
■该研究包括130名个体(47名对照和83名uMD患者)。我们测量了总流体空间(TFS)和内淋巴空间(ELS)体积。我们还评估了ELS/TFS体积比(%)。
■内耳的ELS/TFS体积比，耳蜗,h-PSC患者患侧和对侧的前庭和前庭之间存在显着差异。此外，内耳的ELS/TFS体积比，前庭,h-PSC患者患耳的半圆形管明显高于无h-PSC患者。h-LSC患者患耳的前庭ELS/TFS体积比明显高于无h-LSC患者。
■H-LSC存在于扩展的前庭ELH中。然而,这是内耳ELH进展的结果。
