PDF(Pubmed)
Abstract：
Ochrobactrum species are gram-negative, non-lactose fermenting, aerobic bacilli closely related to Brucella genus. Ochrobactrum intermedium (O. intermedium) is an emergent human pathogen that is difficult to differentiate from other Ochrobactrum species by conventional methods. It is known to infect immunocompromised hosts, has the propensity for abscess formation, and is known for its multidrug resistance. We describe the case of an 84-year-old woman with a background of primary sclerosing cholangitis who presented with fatigue, fever, and syncope. Blood cultures grew O. intermedium. Magnetic resonance cholangiopancreatography and endoscopic retrograde cholangiopancreatography were consistent with cholangitis. Cultures from the biliary duct confirmed the same microorganism. The patient was successfully treated with minocycline. Although rare, O. intermedium should be considered as a differential diagnosis in patients with biliary and gut pathology, particularly in immunocompromised patients.
摘要：
苍白杆菌属革兰氏阴性,非乳糖发酵，与布鲁氏菌属密切相关的需氧杆菌。中间白色芽孢杆菌（O.intermedium）是一种新兴的人类病原体，难以通过常规方法与其他Ocho杆菌属物种区分。已知感染免疫受损的宿主，有脓肿形成的倾向，并以其多重耐药性而闻名。我们描述了一个84岁的女性，其背景是原发性硬化性胆管炎，表现为疲劳，发烧,和晕厥。血培养物生长为O.intermedium。磁共振胰胆管造影术和内镜逆行胰胆管造影术与胆管炎一致。来自胆管的培养物证实了相同的微生物。患者成功接受米诺环素治疗。虽然罕见，O.intermedium应该被认为是胆道和肠道病理患者的鉴别诊断，特别是在免疫功能低下的患者中。
