Abstract：
The study of dementia and epilepsy may provide particular insight into behavioural alterations. We describe a rare case of ictal aggressive behaviour in a patient with focal epilepsy associated with a non-dominant dorso-lateral prefrontal lesion. During focal seizures, our patient showed intense agitation and anger, for a long time misinterpreted as psychogenic attacks, which disappeared after epilepsy surgery. The defined anatomical origin of such ictal emotional behaviour is not fully understood, however, the dorso-lateral prefrontal area appears to correlate less frequently with aggressiveness compared to the antero-mesial area. We describe the electroclinical data of our patient and provide a brief review of the mechanisms underlying aggressive conduct in epilepsy and dementia. An understanding of this mechanism could help to clarify the neural basis and treatment of violence associated with these and other neurological disorders. [Published with video sequence].
摘要：
对痴呆症和癫痫的研究可能会对行为改变提供特别的见解。我们描述了与非显性背外侧前额叶病变相关的局灶性癫痫患者的发作攻击行为的罕见病例。在局灶性癫痫发作期间，我们的病人表现出强烈的激动和愤怒，长期以来被误解为心理攻击，癫痫手术后消失了。尚未完全理解这种发作情绪行为的定义的解剖学起源，然而,与前内侧区域相比，背外侧前额叶区域似乎与侵袭性相关的频率较低。我们描述了患者的临床电数据，并简要回顾了癫痫和痴呆症中攻击性行为的潜在机制。对这种机制的理解可能有助于阐明与这些和其他神经系统疾病相关的暴力的神经基础和治疗。[以视频序列发布]。
