关键词: Elderly Fragilité Frailty Kidney transplantation Mortality Mortalité Sujet âgé Transplantation rénale

Mesh : Aged Comorbidity Humans Kidney Transplantation Tissue Donors Waiting Lists

来  源:   DOI:10.1016/j.nephro.2020.02.007   PDF(Sci-hub)

Abstract:
Age per se should not be a contraindication to kidney transplantation. The first studies have shown a benefit for the survival of elderly eligible patients getting a kidney transplant compared to be maintained on the waiting list. However, more recent data suggest that this benefit is not as constant, notably with a significant early mortality period. The eligibility of elderly patients for transplantation must be based on the usual consideration of co-morbidities, but should also include, for some patients, a geriatric evaluation to detect clinical symptoms of frailty. The decision to transplant an elderly recipient must also integrate the characteristics of the donors, since the use of donors with increasingly expanding criteria can have a negative impact on the survival of these patients.
摘要:
年龄本身不应成为肾移植的禁忌症。第一项研究表明,与等待名单上的患者相比,接受肾脏移植的老年患者的生存受益。然而,最近的数据表明,这种好处并不恒定,特别是有明显的早期死亡率。老年患者移植的资格必须基于通常对合并症的考虑,但也应该包括,对一些病人来说,用于检测虚弱的临床症状的老年评估。移植老年受者的决定还必须结合捐赠者的特点,因为使用标准日益扩大的供体可能会对这些患者的生存产生负面影响。
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