SPOP 通过 DPPA2 的泛素化和降解抑制睾丸生殖细胞肿瘤的进展。
关键词: DPPA2 Degradation SPOP TGCT Ubiquitination
Mesh : Animals Biomarkers, Tumor / metabolism Cell Line, Tumor Cell Proliferation Heterografts Humans Male Mice, Inbred BALB C Mice, Nude Neoplasms, Germ Cell and Embryonal / genetics metabolism pathology Nuclear Proteins / genetics metabolism Proteolysis Repressor Proteins / genetics metabolism Testicular Neoplasms / genetics metabolism pathology Transcription Factors / metabolism Ubiquitination Mice
来 源:
DOI:10.1016/j.bbrc.2021.04.002
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