We searched PubMed, Web of Science, Embase and Cochrane library for eligible studies. The primary outcome was the incidences of complications following FTL. The secondary outcome was the satisfaction rate immediately and 6-month after FTL. The pooled incidences of complications and 95% confidence intervals were estimated using random-effects models.
A total of 26 studies were included in this meta-analysis. Swelling was the most commonly reported complication with a pooled incidence of 35%, followed by skin dimpling (10%), paresthesia (6%), thread visibility/palpability (4%), infection (2%), and thread extrusion (2%). Absorbable threads were associated with a significantly lower risk of paresthesia (3.1% vs. 11.7%) and thread extrusion (1.6% vs. 7.6%) than non-absorbable threads. Patients older than 50 years had a significantly higher risk of dimpling (16% vs. 5.6%) and infection (5.9% vs. 0.7%) than their younger counterparts. In addition, the pooled long-term satisfaction rate was significantly decreased compared to it immediately after FTL (88% vs. 98%).
Non-absorbable threads and older age of patients are associated with higher risks of complications. Therefore, we recommend a judicious use of non-absorbable threads and FLT in older patients. Furthermore, it should be discussed with patients preoperatively that the rejuvenation effect of FTL may not maintain in the long-term.
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我们搜索了PubMed,WebofScience,Embase和Cochrane图书馆用于符合条件的研究。主要结果是FTL后并发症的发生率。次要结果是FTL后立即和6个月的满意率。使用随机效应模型估计并发症的合并发生率和95%置信区间。
本荟萃分析共纳入26项研究。肿胀是最常见的并发症,合并发生率为35%。其次是皮肤凹陷(10%),感觉异常(6%),螺纹可见性/可触及性(4%),感染(2%),和螺纹挤压(2%)。可吸收线与感觉异常的风险显着降低相关(3.1%vs.11.7%)和螺纹挤出(1.6%与7.6%)比不可吸收线。50岁以上的患者患酒窝的风险明显较高(16%vs.5.6%)和感染(5.9%vs.0.7%)比他们的年轻同行。此外,与FTL后立即相比,汇集的长期满意率显著下降(88%与98%)。
不可吸收的线和患者年龄较大与并发症的风险较高相关。因此,我们建议在老年患者中明智地使用不可吸收线和FLT。此外,术前应该与患者讨论,FTL的恢复效果可能无法长期维持。
本期刊要求作者为每篇文章分配一定程度的证据。对于这些循证医学评级的完整描述,请参阅目录或在线作者说明www。springer.com/00266.