Abstract：
The aim of the study was to identify the effectiveness of the continuous passive motion application on clinical outcomes after total knee arthroplasty, based on evidence from recently published high-quality randomized controlled trials.
Two reviewers retrieved platforms of PubMed, Embase, and CENTRAL independently, for identifying eligible randomized controlled trials evaluating the effect of continuous passive motion applied after total knee arthroplasty for knee osteoarthritis. Subgroup meta-analyses were performed for all syntheses based on the follow-up intervals.
A total of 10 randomized controlled trials, involving 841 patients, were finally included. Data were available for 15 different outcomes (including active/passive knee extension/flexion/full range of motion, Western Ontario and McMaster Universities Osteoarthritis Index-pain/physical function/stiffness/total score, visual analogue scale, time up and go, knee girth, Knee Society Scale-function/knee score), at several time points. In general, most of the pools demonstrated similar outcome between continuous passive motion and noncontinuous passive motion groups. Exclusively, the active knee extension at 1 wk (mean difference = 3.00, 95% confidence interval = 0.5-5.5, P = 0.019*), passive knee extension at 1 wk (mean difference = 3.00, 95% confidence interval = 0.28-5.72, P = 0.031*), and 3 mos (mean difference = 3.00, 95% confidence interval = 0.5-5.5, P = 0.019*) were shown to be significantly slightly different between two groups.
This study demonstrated a limited role of continuous passive motion in patients operated with total knee arthroplasty. Thus, there is at this stage no indication for continuous passive motion procedures in patients operated with total knee arthroplasty as a standard postoperative care.
Two reviewers retrieved platforms of PubMed, Embase, and CENTRAL independently, for identifying eligible randomized controlled trials evaluating the effect of continuous passive motion applied after total knee arthroplasty for knee osteoarthritis. Subgroup meta-analyses were performed for all syntheses based on the follow-up intervals.
A total of 10 randomized controlled trials, involving 841 patients, were finally included. Data were available for 15 different outcomes (including active/passive knee extension/flexion/full range of motion, Western Ontario and McMaster Universities Osteoarthritis Index-pain/physical function/stiffness/total score, visual analogue scale, time up and go, knee girth, Knee Society Scale-function/knee score), at several time points. In general, most of the pools demonstrated similar outcome between continuous passive motion and noncontinuous passive motion groups. Exclusively, the active knee extension at 1 wk (mean difference = 3.00, 95% confidence interval = 0.5-5.5, P = 0.019*), passive knee extension at 1 wk (mean difference = 3.00, 95% confidence interval = 0.28-5.72, P = 0.031*), and 3 mos (mean difference = 3.00, 95% confidence interval = 0.5-5.5, P = 0.019*) were shown to be significantly slightly different between two groups.
This study demonstrated a limited role of continuous passive motion in patients operated with total knee arthroplasty. Thus, there is at this stage no indication for continuous passive motion procedures in patients operated with total knee arthroplasty as a standard postoperative care.
摘要：
该研究的目的是确定连续被动运动应用对全膝关节置换术后临床结果的有效性。基于最近发表的高质量随机对照试验的证据.
两位审阅者检索了PubMed的平台，Embase,和中央独立，用于确定合格的随机对照试验，评估全膝关节置换术后应用连续被动运动治疗膝关节骨关节炎的效果。根据随访间隔对所有综合进行亚组荟萃分析。
共10项随机对照试验，涉及841名患者,最终被包括在内。数据可用于15种不同的结果（包括主动/被动膝关节伸展/屈曲/全运动范围，西安大略省和麦克马斯特大学骨关节炎指数-疼痛/身体功能/僵硬/总分，视觉模拟量表,时间过去了，膝盖周长,膝关节社会功能量表/膝关节评分)，在几个时间点。总的来说,大多数池在连续被动运动组和非连续被动运动组之间表现出相似的结果.独家,1周时的主动膝关节伸展（平均差=3.00，95％置信区间=0.5-5.5，P=0.019*），1周时被动膝关节伸展(平均差=3.00,95%置信区间=0.28-5.72,P=0.031*),和3个月（平均差异=3.00，95％置信区间=0.5-5.5，P=0.019*）显示两组之间显着略有不同。
这项研究表明，连续被动运动在全膝关节置换术患者中的作用有限。因此，在这一阶段，对于全膝关节置换术作为标准术后护理的患者，没有连续被动运动程序的指征。
两位审阅者检索了PubMed的平台，Embase,和中央独立，用于确定合格的随机对照试验，评估全膝关节置换术后应用连续被动运动治疗膝关节骨关节炎的效果。根据随访间隔对所有综合进行亚组荟萃分析。
共10项随机对照试验，涉及841名患者,最终被包括在内。数据可用于15种不同的结果（包括主动/被动膝关节伸展/屈曲/全运动范围，西安大略省和麦克马斯特大学骨关节炎指数-疼痛/身体功能/僵硬/总分，视觉模拟量表,时间过去了，膝盖周长,膝关节社会功能量表/膝关节评分)，在几个时间点。总的来说,大多数池在连续被动运动组和非连续被动运动组之间表现出相似的结果.独家,1周时的主动膝关节伸展（平均差=3.00，95％置信区间=0.5-5.5，P=0.019*），1周时被动膝关节伸展(平均差=3.00,95%置信区间=0.28-5.72,P=0.031*),和3个月（平均差异=3.00，95％置信区间=0.5-5.5，P=0.019*）显示两组之间显着略有不同。
这项研究表明，连续被动运动在全膝关节置换术患者中的作用有限。因此，在这一阶段，对于全膝关节置换术作为标准术后护理的患者，没有连续被动运动程序的指征。
