A novel magnetic fluorescent molecularly imprinted sensor for highly selective and sensitive detection of 4-nitrophenol in food samples through a dual-recognition mechanism.

• 影响指数: 9.231
• 发表时间: Jun 2021 30
• 来源期刊: Food Chem
• DOI: 10.1016/j.foodchem.2021.129126
• PMID: 33515947
• 文章类型: Journal Article
• 中科院分区: Q1
• 方向: 医学
• 作者列表: Zhu W,Zhou Y,Liu S,Luo M,Du J,Fan J,Xiong H,Peng H

关键词: 4-Nitrophenol; Dual-recognition; Fe(3)O(4) nanoparticles; Fluorescence sensor; Food sample; Surface imprinting

Mesh: Carbon / chemistry; Food Analysis / methods; Limit of Detection; Magnetics; Molecular Imprinting; Nitrophenols / analysis; Polymers / chemistry; Quantum Dots / chemistry; Reproducibility of Results; Silanes / chemistry; Spectrometry, Fluorescence

Abstract

In this study, surface imprinting, magnetic separation, and fluorescent detection were integrated to develop a dual-recognition sensor (MF-MIPs), which was used for highly selective and sensitive detection of 4-nitrophenol (4-NP) in food samples. Silane-functionalized carbon dots (Si-CDs) participated in the imprinting process and were uniformly distributed into the MIPs layers. MF-MIPs sensor exhibited a high fluorescence response and selectivity based on the dual-recognition mechanism of imprinting recognition and fluorescence identification. The relative fluorescence intensity of MF-MIPs sensor presented a good linear relationship in the range of 0.08-10 μmol·L-1 with a low limit of detection (23.45 nmol·L1) for 4NP. MF-MIPs sensor showed high anti-interference, as well as excellent stability and reusability. The 4-NP recovery from spiked food samples ranged from 93.20 to 102.15%, and the relative standard deviation was lower than 5.0%. Therefore, MF-MIPs sensor may be a promising method for 4-NP detection in food samples.