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Abstract：
Children require transfusion of blood components for a vast array of medical conditions, including acute hemorrhage, hematologic and nonhematologic malignancies, hemoglobinopathy, and allogeneic and autologous stem cell transplant. Evidence-based literature on pediatric transfusion practices is limited, particularly for non-red blood cell products, and many recommendations are extrapolated from studies in adult populations. Recognition of these knowledge gaps has led to increasing numbers of clinical trials focusing on children and establishment of pediatric transfusion working groups in recent years. This article reviews existing literature on pediatric transfusion therapy within the larger context of analogous data in adult populations.
摘要：
儿童需要输血成分以适应各种医疗条件，包括急性出血,血液和非血液恶性肿瘤，血红蛋白病,同种异体和自体干细胞移植。关于儿科输血实践的循证文献有限，特别是对于非红细胞产品，许多建议是从成人人群的研究中推断出来的。对这些知识差距的认识导致近年来越来越多的针对儿童的临床试验和建立儿科输血工作组。本文在成人人群类似数据的更大背景下，回顾了有关儿科输血治疗的现有文献。
