PDF(Pubmed)
Abstract：
Scleredema is a connective tissue disorder that presents as diffuse induration of skin, most often involving the upper body. Scleredema can be associated with prior infection, monoclonal gammopathy, and diabetes mellitus. Pyoderma gangrenosum is a neutrophilic dermatosis that presents as an ulcer with violaceous borders. Pyoderma gangrenosum can be idiopathic or associated with various conditions. A 66-year-old man with a 20-year history of scleredema diabeticorum presented with idiopathic pyoderma gangrenosum in the affected area of scleredema on his neck. His pyoderma gangrenosum resolved after treatment with topical and intralesional corticosteroids. Diseases associated with scleredema, pyoderma gangrenosum or both are reviewed.
摘要：
Screedema是一种结缔组织疾病，表现为皮肤弥漫性硬结，通常涉及上半身。Scleedema可能与先前的感染有关，单克隆丙种球蛋白病，和糖尿病。坏疽性脓皮病是一种嗜中性皮肤病，表现为具有暴力边界的溃疡。坏疽性脓皮病可以是特发性的或与各种疾病有关。一名有20年糖尿病硬肿症病史的66岁男子在其颈部硬肿症的受影响区域出现特发性坏疽性脓皮病。他的坏疽性脓皮病在局部和病灶内皮质类固醇治疗后消退。与硬肿症相关的疾病，坏疽性脓皮病或两者都进行审查。
