PDF(Sci-hub)
Abstract：
Two main objectives were established. First objective was to determine the prevalence of the cleft lip and/or cleft palate (CL/P) in Thailand from 2012 to 2015 using the orofacial clefts (OFCs) registry and civil registration. Second objective was to conduct a quality control of this OFC registry especially for the Birth Defects Registration (BDR).
Registry-based survey.
Analyzing data from the Thailand National Health Security Office.
Registered patients with CL/P in Thailand from 2012 to 2015.
None.
Duplicated records were verified using National Identity Number (Thai ID#) and date of birth. The prevalence of CL/P and specific phenotypes was then calculated. From this prevalence estimate method, quality assurance of the OFCs registry was possible.
For the main outcome, the population-weighted pool prevalence of CL/P was 2.14 per 1000 live births (95% confidence interval of 2.08-2.20). Thai ID# and expense reimbursement systems were the main factors driving this cases capturing. However, this OFCs registration still requires active case finding with clinical verification, improvement of staff training and databases networking.
This study reported a very high CL/P prevalence of Thailand. Strengths and limitations of these OFCs registry and BDR were described.
Registry-based survey.
Analyzing data from the Thailand National Health Security Office.
Registered patients with CL/P in Thailand from 2012 to 2015.
None.
Duplicated records were verified using National Identity Number (Thai ID#) and date of birth. The prevalence of CL/P and specific phenotypes was then calculated. From this prevalence estimate method, quality assurance of the OFCs registry was possible.
For the main outcome, the population-weighted pool prevalence of CL/P was 2.14 per 1000 live births (95% confidence interval of 2.08-2.20). Thai ID# and expense reimbursement systems were the main factors driving this cases capturing. However, this OFCs registration still requires active case finding with clinical verification, improvement of staff training and databases networking.
This study reported a very high CL/P prevalence of Thailand. Strengths and limitations of these OFCs registry and BDR were described.
摘要：
确定了两个主要目标。第一个目标是使用口面裂痕（OFC）登记和民事登记来确定2012年至2015年泰国唇裂和/或腭裂（CL/P）的患病率。第二个目标是对该OFC注册表进行质量控制，尤其是出生缺陷注册（BDR）。
基于注册表的调查。
分析泰国国家卫生安全局的数据。
2012年至2015年在泰国注册的CL/P患者。
无。
使用国民身份证号码（泰国身份证号码）和出生日期验证了重复记录。然后计算CL/P和特定表型的患病率。从这种患病率估计方法来看，OFC注册的质量保证是可能的。
对于主要结果，CL/P的人群加权池患病率为2.14/1,000活产(95%置信区间为2.08~2.20).泰国身份证号码和费用报销系统是推动这一案件捕获的主要因素。然而,这种OFC注册仍然需要积极的病例发现和临床验证，改善员工培训和数据库联网。
这项研究报道了泰国非常高的CL/P患病率。描述了这些OFCs注册表和BDR的优势和局限性。
基于注册表的调查。
分析泰国国家卫生安全局的数据。
2012年至2015年在泰国注册的CL/P患者。
无。
使用国民身份证号码（泰国身份证号码）和出生日期验证了重复记录。然后计算CL/P和特定表型的患病率。从这种患病率估计方法来看，OFC注册的质量保证是可能的。
对于主要结果，CL/P的人群加权池患病率为2.14/1,000活产(95%置信区间为2.08~2.20).泰国身份证号码和费用报销系统是推动这一案件捕获的主要因素。然而,这种OFC注册仍然需要积极的病例发现和临床验证，改善员工培训和数据库联网。
这项研究报道了泰国非常高的CL/P患病率。描述了这些OFCs注册表和BDR的优势和局限性。
