Abstract:
Necrotizing enterocolitis (NEC) is a devastating gastrointestinal disease of neonates, especially of preterm infants, with high morbidity and mortality. The surviving infants may have digestive tract and neurological sequelae. Therefore, the prevention and treatment of NEC are of great significance in improving survival rate and survival quality of neonates. To provide evidence-based recommendations for management of NEC, the guidelines were developed based on the Grading of Recommendations Assessment, Development and Evaluation (GRADE) and the current domestic and overseas studies.
摘要:
坏死性小肠结肠炎(NEC)是一种毁灭性的新生儿胃肠道疾病,尤其是早产儿,高发病率和死亡率。存活的婴儿可能有消化道和神经系统后遗症。因此,NEC的防治对提高新生儿生存率和生存质量具有重要意义。为NEC的管理提供循证建议,准则是根据建议评估的分级制定的,发展与评价(GRADE)和当前国内外研究。