来自不同长度序列的 KRAS 启动子 G - 四体复合物 : 物理化学研究。
关键词: CD spectroscopy KRAS G-quadruplex differential scanning calorimetry thermodynamic stability
Mesh : Acridines / pharmacology Antineoplastic Agents / pharmacology Binding Sites / genetics Calorimetry, Differential Scanning / methods Circular Dichroism DNA / genetics G-Quadruplexes Guanine / metabolism Humans Magnetic Resonance Spectroscopy / methods Oncogenes / genetics Porphyrins / pharmacology Promoter Regions, Genetic / genetics Proto-Oncogene Mas Proto-Oncogene Proteins p21(ras) / genetics Thermodynamics
来 源:
DOI:10.3390/ijms22010448
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