关键词: Madurella mycetomatis clinical presentation eumycetoma multiple lesions mycetoma

Mesh : Female Humans Madurella Mycetoma / diagnosis Sudan

来  源:   DOI:10.1093/trstmh/traa164

Abstract:
In this communication, we report on the first-ever patient presenting with 17 lesions of Madurella mycetomatis eumycetoma in different parts of the body. The reported patient is a 15-y-old female who presented to the Mycetoma Research Centre, University of Khartoum, Khartoum, Sudan, in 2017 with recurrent back and anterior abdominal wall eumycetoma lesions. They were surgically excised, and during the course of follow-up, she developed 15 other eumycetoma lesions, scattered mostly on her upper and lower limbs and gluteal region. The diagnosis of Madurella mycetomatis was confirmed by molecular identification of grains and culture, histopathological examination and ultrasound examination. The cause and the explanation of such a presentation in puzzling; it is not due to multiple subcutaneous implantations because of the lack of history of relevant local trauma. Lymphatic spread is unlikely as the distribution of the lesions is not in line with this. Haematogenous spread is a possible explanation. This rare presentation of eumycetoma poses a great challenge for diagnosis and management.
摘要:
在这份通讯中,我们报道了首例患者在身体不同部位出现17例machurellamycetomatiseumycetoma病变。报告的患者是一名15岁的女性,她被送往Mycetoma研究中心,喀土穆大学,喀土穆,苏丹,2017年复发的背部和前腹壁腺瘤病变。他们被手术切除了,在后续过程中,她发展了另外15个Eumycetoma病变,主要散布在她的上肢和下肢以及臀区。通过对谷物和培养物的分子鉴定证实了mycetomatis的诊断,组织病理学检查和超声检查。这种表现的原因和解释令人困惑;这不是由于多次皮下植入,因为缺乏相关的局部创伤史。淋巴扩散不太可能,因为病变的分布与此不符。血源性传播是一种可能的解释。Eumycetoma的这种罕见表现对诊断和治疗提出了巨大挑战。
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