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Abstract：
Explanted tissues from vertebrate embryos reliably develop in culture and have provided essential paradigms for understanding embryogenesis, from early embryological investigations of induction, to the extensive study of Xenopus animal caps, to the current studies of mammalian gastruloids. Cultured explants of the Xenopus dorsal marginal zone (\"Keller\" explants) serve as a central paradigm for studies of convergent extension cell movements, yet we know little about the global patterns of gene expression in these explants.
In an effort to more thoroughly develop this important model system, we provide here a time-resolved bulk transcriptome for developing Keller explants.
The dataset reported here provides a useful resource for those using Keller explants for studies of morphogenesis and provide genome-scale insights into the temporal patterns of gene expression in an important tissue when explanted and grown in culture.
In an effort to more thoroughly develop this important model system, we provide here a time-resolved bulk transcriptome for developing Keller explants.
The dataset reported here provides a useful resource for those using Keller explants for studies of morphogenesis and provide genome-scale insights into the temporal patterns of gene expression in an important tissue when explanted and grown in culture.
摘要：
来自脊椎动物胚胎的移植组织在培养中可靠地发育，并为理解胚胎发生提供了必要的范例。从诱导的早期胚胎学研究中，对非洲爪狼动物帽的广泛研究，目前对哺乳动物类动物的研究。非洲爪狼背边缘区的培养外植体（“凯勒”外植体）是研究收敛延伸细胞运动的中心范例，然而，我们对这些外植体中基因表达的整体模式知之甚少。
为了更彻底地开发这个重要的模型系统，我们在这里提供了一个时间分辨的批量转录组，用于开发凯勒外植体。
这里报道的数据集为那些使用凯勒外植体进行形态发生研究的人提供了有用的资源，并提供了基因组规模的见解，以了解重要组织中外植和培养时基因表达的时间模式。
为了更彻底地开发这个重要的模型系统，我们在这里提供了一个时间分辨的批量转录组，用于开发凯勒外植体。
这里报道的数据集为那些使用凯勒外植体进行形态发生研究的人提供了有用的资源，并提供了基因组规模的见解，以了解重要组织中外植和培养时基因表达的时间模式。
