cMET 通过抑制 RKIP 促进大肠癌转移和上皮间质转化。
关键词: EMT RKIP cMET colorectal cancer metastasis
Mesh : Aged Animals Cell Line, Tumor Cell Movement / genetics Cell Proliferation / genetics Colorectal Neoplasms / genetics metabolism pathology Down-Regulation / genetics Epithelial-Mesenchymal Transition / genetics Female Gene Expression Regulation, Neoplastic Gene Knockdown Techniques Humans Kaplan-Meier Estimate Liver Neoplasms / secondary MAP Kinase Signaling System Male Mice, Inbred BALB C Mice, Nude Middle Aged Neoplasm Invasiveness Neoplasm Metastasis Phosphatidylethanolamine Binding Protein / metabolism Proto-Oncogene Proteins c-met / metabolism Mice
来 源:
DOI:10.1002/jcp.30142
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