非核糖体肽合成酶 BpsA 的定向进化 , 以使人类磷酸蒽环酰转移酶能够识别抗生素候选物。
关键词: 4′-phosphopantetheinyl transferase NRPS Type II PPTase aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase antibiotic screening indigoidine
Mesh : Animals Anti-Bacterial Agents / pharmacology Bacterial Proteins Humans Peptide Synthases / genetics Rats Transferases (Other Substituted Phosphate Groups) / genetics
来 源:
DOI:10.1021/acsinfecdis.0c00606
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