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Abstract：
Three-dimensional (3D) printing technologies have been widely used to manufacture crowns and frameworks for fixed dental prostheses. This systematic review and meta-analysis aimed to assess the reliability of the marginal fit of 3D-printed cobalt-chromium-based fixed dental prostheses in comparison to conventional casting methods. Articles published until 25 June 2020, reporting the marginal fit of fixed prostheses fabricated with metal 3D printing, were searched using electronic literature databases. After the screening and quality assessment, 21 eligible peer-reviewed articles were selected. Meta-analysis revealed that the marginal gap of the prostheses manufactured using 3D printing was significantly smaller compared to that manufactured using casting methods (standard mean difference (95% CI): -0.92 (-1.45, -0.38); Z = -3.37; p = 0.0008). The estimated difference between the single and multi-unit types did not differ significantly (p = 0.3573). In the subgroup analysis for the measurement methods, the tendency of marginal discrepancy between the 3D printing and casting groups was significantly different between articles that used direct observation and those that used the silicone replica technique (p < 0.001). Metal 3D printing technologies appear reliable as an alternative to casting methods in terms of the fit of the fixed dental prostheses. In order to analyze the factors influencing manufacturing and confirm the results of this review, further controlled laboratory and clinical studies are required.
摘要：
背景技术三维(3D)打印技术已经被广泛地用于制造用于固定牙齿假体的牙冠和框架。此系统综述和荟萃分析旨在评估与传统铸造方法相比，3D打印钴铬基固定假牙的边缘配合的可靠性。直到2020年6月25日发表的文章，报告了用金属3D打印制造的固定假体的边际配合，使用电子文献数据库进行检索。经过筛选和质量评估，选择了21篇合格的同行评审文章。荟萃分析显示，与使用铸造方法制造的假体相比，使用3D打印制造的假体的边缘间隙明显较小（标准平均差（95％CI）：-0.92（-1.45，-0.38）;Z=-3.37;p=0.0008）。单单元和多单元类型之间的估计差异没有显着差异（p=0.3573）。在子群分析的测量方法中，3D打印组和铸造组之间的边际差异趋势在使用直接观察的文章和使用硅胶复制技术的文章之间存在显着差异（p<0.001）。就固定假牙的配合而言，金属3D打印技术作为铸造方法的替代方法似乎是可靠的。为了分析影响制造业的因素并证实本综述的结果，需要进一步的受控实验室和临床研究。
