关键词: Heck's disease focal epithelial hyperplasia human papilloma virus immunosuppression multifocal epithelial hyperplasia organ transplant

Mesh : African Americans Aged Focal Epithelial Hyperplasia Humans Hyperplasia Lung Transplantation Male Papillomaviridae

来  源:   DOI:10.1111/tid.13497   PDF(Sci-hub)

Abstract:
Oral multifocal epithelial hyperplasia (MEH), or Heck\'s disease, is a rare benign proliferation of the oral mucosa associated with human papillomavirus (HPV). It clinically presents as multiple asymptomatic papules and nodules that mostly affect the lips, buccal mucosa, and tongue. MEH is predominantly found in children and young adults while relatively few cases have been reported in the elderly population. Here, we report a case of oral MEH in a 65-year-old man with history of lung transplantation. This case highlights the potential susceptibility of organ transplant recipients to the development of MEH. Since MEH that does not require treatment unless the lesion bothers the patient, clinicians should promptly establish a definitive diagnosis to rule out other HPV-related precancerous lesions.
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