超分辨率成像揭示了融合蛋白和转录对 CTCF 组织的相反作用。
关键词: CTCF Pol II chromatin cohesin quantitative analysis super-resolution imaging topological associated domain transcription
Mesh : Animals CCCTC-Binding Factor / genetics metabolism Cell Cycle Proteins / genetics metabolism Cells, Cultured Chromatin / genetics metabolism Chromosomal Proteins, Non-Histone / genetics metabolism Chromosomes, Mammalian Embryonic Stem Cells / cytology metabolism Genetic Loci Genome Image Processing, Computer-Assisted Mice Microscopy, Fluorescence / methods Proteins / genetics metabolism Transcription, Genetic Cohesins
来 源:
DOI:10.1016/j.molcel.2020.10.001
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