Mesh : Child Consensus Humans Kidney Neoplasms / pathology radiotherapy Organ Sparing Treatments / methods Practice Guidelines as Topic Radiologic Health Radiotherapy, Conformal / methods trends

来  源:   DOI:10.1016/S2352-4642(20)30183-8   PDF(Sci-hub)

Abstract:
For decades, radiotherapy with two opposing photon beams has been the standard technique used to cover the flank target volume in paediatric patients with renal tumours. Nowadays, many institutes are implementing advanced radiotherapy techniques that spare healthy tissue. To decrease the radiotherapy dose to healthy structures while preserving oncological efficacy, the conventional approach of flank irradiation has been adapted into a guideline for highly conformal flank target-volume delineation by paediatric radiation oncologists and representatives of the International Society of Paediatric Oncology\'s Renal Tumour Study Group (SIOP-RTSG) board during four live international consensus meetings. The consensus was refined by delineation exercises and videoconferences by ten collaborating paediatric radiation oncologists. The final guideline includes eight chronological steps to generate the tumour bed and clinical, internal, and planning target volumes, and it describes the optional use of surgical clips to optimise treatment planning. This guideline will be added into the radiotherapy guideline of the UMBRELLA SIOP-RTSG protocol for paediatric renal tumours to improve international consistency of highly conformal flank target-volume delineation.
摘要:
几十年来,使用两个相反的光子束进行放射疗法是用于覆盖患有肾脏肿瘤的儿科患者的侧腹靶体积的标准技术。如今,许多机构正在实施先进的放射治疗技术,以节省健康组织。减少对健康结构的放疗剂量,同时保持肿瘤疗效,儿科放射肿瘤学家和国际儿科肿瘤学会肾肿瘤研究组(SIOP-RTSG)委员会的代表在四次现场国际共识会议期间,将传统的侧腹照射方法调整为高度适形侧腹靶体积勾画指南.通过十位合作的儿科放射肿瘤学家的划界练习和视频会议,完善了共识。最终指南包括八个按时间顺序排列的步骤来生成肿瘤床和临床,内部,和规划目标卷,它描述了手术夹的可选使用,以优化治疗计划。该指南将被添加到儿科肾肿瘤UMBRELLASIOP-RTSG方案的放疗指南中,以提高高度适形侧腹靶体积勾画的国际一致性。
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