关键词: Anti-inflammatory agents Anticoagulants Antiplatelet agent Guideline Peptic ulcer non-steroidal

Mesh : Anti-Inflammatory Agents / adverse effects therapeutic use Anticoagulants / adverse effects therapeutic use Cyclooxygenase 2 Inhibitors / therapeutic use Endoscopy, Gastrointestinal Helicobacter Infections / diagnosis drug therapy Hemorrhage / complications therapy Humans Peptic Ulcer / diagnosis etiology prevention & control Platelet Aggregation Inhibitors / adverse effects therapeutic use Proton Pump Inhibitors / therapeutic use

来  源:   DOI:10.4166/kjg.2020.76.3.108

Abstract:
The Korean guidelines for nonsteroidal anti-inflammatory drug (NSAID)-induced peptic ulcers were previously developed under co-work with the Korean College of Helicobacter and Upper Gastrointestinal Research and Korean Society of Gastroenterology at 2009. On the other hand, the previous guidelines were based mainly on a literature review and expert opinions. Therefore, the guidelines need to be revised. In this study, a guideline development committee for drug-induced peptic ulcers was organized under the Korean College of Helicobacter and Upper Gastrointestinal Research in 2017. Nine statements were developed, including four for NSAID, three for aspirin and other antiplatelet agents, and two for anticoagulants through de novo processes based on evidence-based medicine, such as a literature search, meta-analysis, and the consensus was established using the modified Delphi method. The primary target of this guideline was adult patients taking long-term NSAIDs, aspirin, or other antiplatelet agent and anticoagulants. The revised guidelines reflect the consensus of expert opinions and are intended to assist relevant clinicians in the management and prevention of drug-induced peptic ulcers and associated conditions.
摘要:
韩国非甾体抗炎药(NSAID)引起的消化性溃疡的指南先前是与韩国螺杆菌和上消化道研究学院以及韩国胃肠病学会于2009年共同制定的。另一方面,以前的指南主要基于文献综述和专家意见。因此,准则需要修订。在这项研究中,2017年,韩国幽门螺杆菌和上消化道研究学院成立了药物引起的消化性溃疡指南制定委员会.发表了九项声明,包括四例非甾体抗炎药,三种用于阿司匹林和其他抗血小板药物,和两个抗凝剂通过基于循证医学的从头过程,比如文献检索,荟萃分析,并使用改进的德尔菲法建立共识。该指南的主要目标是长期服用NSAIDs的成年患者,阿司匹林,或其他抗血小板剂和抗凝剂。修订后的指南反映了专家意见的共识,旨在帮助相关临床医生管理和预防药物引起的消化性溃疡和相关疾病。
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