Abstract：
Moxifloxacin is a third-generation fluoroquinolone antibiotic with broad spectrum activity and also used as component of anti-tubercular therapy (ATT). Though frequently prescribed, moxifloxacin induced encephalopathy is uncommonly seen. Here we describe a forty four year old male, with features of disseminated tuberculosis (TB) and suspected case of multi-drug resistance (MDR), who developed acute encephalopathy. Extensive laboratory investigations, neuroimaging of brain, cerebrospinal fluid analysis was unremarkable. On stopping moxifloxacin, which was being administerd as part of ATT for MDR TB, encephalopathy resolved completely, thereby proving it to be a case of moxifloxacin induced encephalopathy. To conclude, by presenting this case, we wish to raise awareness about moxifloxacin induced encephalopathy among healthcare providers.
摘要：
莫西沙星是第三代氟喹诺酮类抗生素，具有广谱活性，也用作抗结核治疗（ATT）的组成部分。虽然经常开处方，莫西沙星引起的脑病并不常见。这里我们描述了一个四十四岁的男性，具有播散性结核病（TB）和多药耐药（MDR）疑似病例的特征，患上了急性脑病.广泛的实验室调查，大脑的神经成像，脑脊液分析无异常。在停止莫西沙星时，作为耐多药结核病ATT的一部分，脑病完全缓解，从而证明它是莫西沙星诱发的脑病。最后，通过介绍这个案例，我们希望提高医疗保健提供者对莫西沙星诱发脑病的认识。
