关键词: alignment co-attraction collective migration contact inhibition of locomotion neural crest supracellular

Mesh : Animal Migration Animals Antelopes / physiology Cell Movement Embryonic Stem Cells / physiology Neural Crest / physiology

来  源:   DOI:10.1098/rstb.2019.0387   PDF(Sci-hub)   PDF(Pubmed)

Abstract:
Collective migration, the movement of groups in which individuals affect the behaviour of one another, occurs at practically every scale, from bacteria up to whole species\' populations. Universal principles of collective movement can be applied at all levels. In this review, we will describe the rules governing collective motility, with a specific focus on the neural crest, an embryonic stem cell population that undergoes extensive collective migration during development. We will discuss how the underlying principles of individual cell behaviour, and those that emerge from a supracellular scale, can explain collective migration. This article is part of the theme issue \'Multi-scale analysis and modelling of collective migration in biological systems\'.
摘要:
集体移徙,个体影响彼此行为的群体的运动,几乎发生在每个尺度上,从细菌到整个物种的种群。集体运动的普遍原则可以在各级应用。在这次审查中,我们将描述管理集体活动的规则,特别关注神经峰,在发育过程中经历广泛的集体迁移的胚胎干细胞群。我们将讨论单个细胞行为的基本原理,那些从超细胞尺度出现的,可以解释集体迁移。本文是“生物系统中集体迁移的多尺度分析和建模”主题的一部分。
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