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Abstract：
The extradural neural axis compartment (EDNAC) is an adipovenous zone located between the meningeal and endosteal layers of the dura and has been minimally investigated. It runs along the neuraxis from the orbits down to the coccyx and contains fat, valveless veins, arteries, and nerves. In the present review, we have outlined the current knowledge regarding the structural and functional significance of the EDNAC.
We performed a narrative review of the reported EDNAC data.
The EDNAC can be organized into 4 regional enlargements along its length: the orbital, lateral sellar, clival, and spinal segments, with a lateral sellar orbital junction linking the orbital and lateral sellar segments. The orbital EDNAC facilitates the movement of the eyeball and elsewhere allows limited motility for the meningeal dura. The major nerves and vessels are cushioned and supported by the EDNAC. Increased intra-abdominal pressure will also be conveyed along the spinal EDNAC, causing increased venous pressure in the spine and cranium. From a pathological perspective, the EDNAC functions as a low-resistance, extradural passageway that might facilitate tumor encroachment and expansion.
Clinicians should be aware of the extent and significance of the EDNAC, which could affect skull base and spine surgery, and have an understanding of the tumor spread pathways and growth patterns. Comparatively little research has focused on the EDNAC since its initial description. Therefore, future investigations are required to provide more information on this underappreciated component of neuraxial anatomy.
We performed a narrative review of the reported EDNAC data.
The EDNAC can be organized into 4 regional enlargements along its length: the orbital, lateral sellar, clival, and spinal segments, with a lateral sellar orbital junction linking the orbital and lateral sellar segments. The orbital EDNAC facilitates the movement of the eyeball and elsewhere allows limited motility for the meningeal dura. The major nerves and vessels are cushioned and supported by the EDNAC. Increased intra-abdominal pressure will also be conveyed along the spinal EDNAC, causing increased venous pressure in the spine and cranium. From a pathological perspective, the EDNAC functions as a low-resistance, extradural passageway that might facilitate tumor encroachment and expansion.
Clinicians should be aware of the extent and significance of the EDNAC, which could affect skull base and spine surgery, and have an understanding of the tumor spread pathways and growth patterns. Comparatively little research has focused on the EDNAC since its initial description. Therefore, future investigations are required to provide more information on this underappreciated component of neuraxial anatomy.
摘要：
硬膜外神经轴室（EDNAC）是位于硬膜的脑膜和内膜层之间的脂肪静脉区，并且已经进行了最少的研究。它沿着神经轴从轨道向下延伸到尾骨，含有脂肪，无瓣静脉,动脉,和神经。在本次审查中，我们概述了目前有关EDNAC结构和功能意义的知识。
我们对报告的EDNAC数据进行了叙述性回顾。
EDNAC沿其长度可以分为4个区域扩展：轨道，外侧鞍区,clival,和脊柱节段，有一个外侧鞍眶交界处，连接眶段和外侧鞍段。眼眶EDNAC促进眼球的运动，在其他地方允许脑膜硬膜的有限运动性。主要神经和血管由EDNAC缓冲和支撑。增加的腹内压也将沿着脊髓EDNAC传递，导致脊柱和头颅静脉压升高.从病理学的角度来看,EDNAC的功能是低电阻，可能促进肿瘤侵蚀和扩张的硬膜外通道。
临床医生应该意识到EDNAC的程度和意义，这可能会影响颅底和脊柱手术，了解肿瘤的扩散途径和生长模式。自最初描述以来，很少有研究集中在EDNAC上。因此,未来的研究需要提供更多的信息，关于这个未被重视的神经轴解剖的组成部分。
我们对报告的EDNAC数据进行了叙述性回顾。
EDNAC沿其长度可以分为4个区域扩展：轨道，外侧鞍区,clival,和脊柱节段，有一个外侧鞍眶交界处，连接眶段和外侧鞍段。眼眶EDNAC促进眼球的运动，在其他地方允许脑膜硬膜的有限运动性。主要神经和血管由EDNAC缓冲和支撑。增加的腹内压也将沿着脊髓EDNAC传递，导致脊柱和头颅静脉压升高.从病理学的角度来看,EDNAC的功能是低电阻，可能促进肿瘤侵蚀和扩张的硬膜外通道。
临床医生应该意识到EDNAC的程度和意义，这可能会影响颅底和脊柱手术，了解肿瘤的扩散途径和生长模式。自最初描述以来，很少有研究集中在EDNAC上。因此,未来的研究需要提供更多的信息，关于这个未被重视的神经轴解剖的组成部分。
