凝聚素依赖性和非依赖性机制介导启动子和增强子之间的染色体接触。
关键词: CTCF SLAM-seq cohesin promoter capture Hi-C promoter-enhancer interactions transcriptional regulation
Mesh : Cell Cycle Proteins / metabolism Chromatin Chromosomal Proteins, Non-Histone / metabolism Chromosomes / metabolism DNA-Binding Proteins / metabolism Enhancer Elements, Genetic / genetics Gene Expression Regulation HeLa Cells Humans Promoter Regions, Genetic Transcription, Genetic Cohesins
来 源:
DOI:10.1016/j.celrep.2020.107929
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