关键词: apoptotic injury bupivacaine manganese superoxide dismutase oxidative stress reactive oxygen species
Mesh : Acetylcysteine / administration & dosage Animals Anthracenes / administration & dosage Antioxidants / administration & dosage Bupivacaine / administration & dosage toxicity Cell Line, Tumor Cyclic N-Oxides / administration & dosage Disease Models, Animal Gene Knockdown Techniques Humans Injections, Spinal JNK Mitogen-Activated Protein Kinases / antagonists & inhibitors genetics metabolism MAP Kinase Signaling System / drug effects genetics Male Mitochondria / drug effects pathology Neurons / cytology drug effects pathology Neurotoxicity Syndromes / etiology pathology prevention & control Oxidative Stress / drug effects RNA, Small Interfering / metabolism Rats Reactive Oxygen Species / metabolism Superoxide Dismutase / genetics metabolism Transcriptional Activation / drug effects genetics
来 源:
DOI:10.18632/aging.103447
PDF(Pubmed)