人 18S rRNA 甲基转移酶 DIMT1 在核糖体组装和翻译中的结构和催化作用。
关键词: 18S rRNA DIMT1 E85A DNA damage response RNA methylation RNA-modifying enzyme cancer catalytic role dimethyladenosine transferase 1 (DIMT1) enzyme rRNA ribosome assembly ribosome biogenesis structural biology translation control translation fidelity
Mesh : Amino Acid Substitution Catalysis Crystallography, X-Ray HEK293 Cells Humans Methyltransferases / chemistry genetics metabolism Mutation, Missense Protein Biosynthesis RNA, Ribosomal, 18S / chemistry genetics metabolism Ribosome Subunits, Small, Eukaryotic / chemistry genetics metabolism
来 源:
DOI:10.1074/jbc.RA120.014236
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