关键词: Brain metastases Brain tumors CART-T cell Immunotherapies Neurologic complications Neurotoxicity

Mesh : Brain Neoplasms / complications therapy Central Nervous System Neoplasms Hospitalists Humans Immunotherapy / adverse effects Neurology

来  源:   DOI:10.1007/s11910-020-01056-0   PDF(Sci-hub)

Abstract:
Patients with brain tumors presenting to the emergency room with acute neurologic complications may warrant urgent investigations and emergent management. As the neuro-hospitalist will likely encounter this complex patient population, an understanding of the acute neurologic issues will have value.
We discuss updated information and management regarding various acute neurologic complications among neuro-oncology patients and neurologic complications of immunotherapy. Understanding of the acute neurologic complications associated with central nervous system tumors and with common contemporary cancer treatments will facilitate the neuro-hospitalist management of these patient populations. While there are aspects analogous to the diagnosis and management in the non-oncologic population, a number of unique features discussed in this review should be considered.
摘要:
患有脑肿瘤并出现急性神经系统并发症的急诊室患者可能需要紧急调查和紧急处理。由于神经住院医师可能会遇到这个复杂的患者群体,对急性神经问题的理解将有价值。
我们讨论了关于神经肿瘤患者中各种急性神经系统并发症和免疫治疗神经系统并发症的最新信息和管理。了解与中枢神经系统肿瘤和当代常见癌症治疗相关的急性神经系统并发症将有助于这些患者人群的神经医院管理。虽然有一些方面类似于非肿瘤人群的诊断和管理,应考虑本综述中讨论的许多独特功能。
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