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Abstract：
The recent outbreak in severe acute respiratory syndrome - coronavirus-2 (SARS-CoV-2) has demonstrated the complete inability of nations across the world to cope with the pressures of a global pandemic, especially one in which the only current feasible treatments are those which deal with the symptoms alone and not the viral cause. As the death toll rises, scientists begin to fall toward new avenues of research, with novelty showing itself to be an incredible and so far, underrated resource. In this case, the use of biosurfactants in dealing with this pandemic justifies extensive study with their potential applications being in the prevention of viral spread; dealing with the symptoms that develop after the incubation period; directly targeting viral infected cells and preventing the spread of the virus throughout the host, all in addition to also acting as potential drug delivery systems and cleaning agents. This extensive avenue of biosurfactants owes to the simplicity in their amphiphilic structure which permits them to interact directly with the lipid membrane of the coronavirus, in a way which wouldn\'t be of significant threat to the host. Although it could possibly interact and affect the virus, it could also affect human internal organs/cells by interacting with lipid membrane, if (biosurfactant is) ingested, and it still needs further studies in human models. The structure of the coronavirus, in this case SARS-CoV-2, is detrimentally dependent on the integrity of its lipid membrane which encloses its vital proteins and RNA. Biosurfactants possess the innate ability to threaten this membrane, a result of their own hydrophobic domains across their amphiphilic structure. With biosurfactants additionally being both natural and sustainable, while also possessing a remarkably low cytotoxicity, it is of no doubt that they are going to be of increasing significance in dealing with the current pandemic.
摘要：
最近爆发的严重急性呼吸系统综合症-冠状病毒-2（SARS-CoV-2）表明，世界各国完全无力应对全球大流行的压力，尤其是目前唯一可行的治疗方法是那些单独处理症状而不是病毒病因的治疗方法。随着死亡人数的上升,科学家开始转向新的研究途径，到目前为止，新颖性令人难以置信，被低估的资源。在这种情况下,使用生物表面活性剂应对这种大流行证明了广泛的研究，它们的潜在应用是预防病毒传播;处理潜伏期后出现的症状;直接针对病毒感染的细胞，防止病毒在整个宿主中的传播，除了作为潜在的药物输送系统和清洁剂。生物表面活性剂的这种广泛途径归因于其两亲结构的简单性，这使得它们可以直接与冠状病毒的脂质膜相互作用。以一种不会对主机造成重大威胁的方式。尽管它可能会相互作用并影响病毒，它还可以通过与脂质膜相互作用影响人体内部器官/细胞，如果（生物表面活性剂）摄入，它还需要在人体模型中进一步研究。冠状病毒的结构，在这种情况下,SARS-CoV-2不利地依赖于其包围其重要蛋白质和RNA的脂质膜的完整性。生物表面活性剂具有威胁这种膜的先天能力，由于它们自己的疏水结构域穿过它们的两亲结构。此外，生物表面活性剂既是天然的又是可持续的，同时还具有极低的细胞毒性，毫无疑问，它们在应对当前的大流行方面将越来越重要。
