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Abstract：
BACKGROUND: Necrotising otitis externa is a progressive infection of the external auditory canal which extends to affect the temporal bone and adjacent structures. Progression of the disease process can result in serious sequelae, including cranial nerve palsies and death. There is currently no formal published treatment guideline.
OBJECTIVE: This study aimed to integrate current evidence and data from our own retrospective case series in order to develop a guideline to optimise necrotising otitis externa patient management.
METHODS: A retrospective review of necrotising otitis externa cases within NHS Lothian, Scotland, between 2013 and 2018, was performed, along with a PubMed review.
RESULTS: Prevalent presenting signs, symptoms and patient demographic data were established. Furthermore, features of cases associated with adverse outcomes were defined. A key feature of the guideline is defining at-risk patients with initial intensive treatment. Investigations and outcomes are assessed and treatment adjusted appropriately.
CONCLUSIONS: This multi-departmental approach has facilitated the development of a succinct, systematic guideline for the management of necrotising otitis externa. Initial patient outcomes appear promising.
OBJECTIVE: This study aimed to integrate current evidence and data from our own retrospective case series in order to develop a guideline to optimise necrotising otitis externa patient management.
METHODS: A retrospective review of necrotising otitis externa cases within NHS Lothian, Scotland, between 2013 and 2018, was performed, along with a PubMed review.
RESULTS: Prevalent presenting signs, symptoms and patient demographic data were established. Furthermore, features of cases associated with adverse outcomes were defined. A key feature of the guideline is defining at-risk patients with initial intensive treatment. Investigations and outcomes are assessed and treatment adjusted appropriately.
CONCLUSIONS: This multi-departmental approach has facilitated the development of a succinct, systematic guideline for the management of necrotising otitis externa. Initial patient outcomes appear promising.
摘要：
背景：坏死性外耳炎是外耳道的进行性感染，其延伸影响颞骨和邻近结构。疾病进程的进展可导致严重的后遗症，包括脑神经麻痹和死亡.目前没有正式公布的治疗指南。
目的：本研究旨在整合现有证据和我们自己的回顾性病例系列数据，以制定优化坏死性外耳炎患者管理的指南。
方法：对NHSLothian内坏死性外耳炎病例的回顾性回顾，苏格兰,在2013年至2018年期间，以及PubMed评论。
结果：普遍出现迹象，建立症状和患者人口统计学数据.此外，定义了与不良结局相关的病例特征.该指南的一个关键特征是定义初始强化治疗的高危患者。评估调查和结果，并适当调整治疗。
结论：这种多部门方法促进了简洁，坏死性外耳道炎管理的系统指南。最初的患者结果似乎很有希望。
目的：本研究旨在整合现有证据和我们自己的回顾性病例系列数据，以制定优化坏死性外耳炎患者管理的指南。
方法：对NHSLothian内坏死性外耳炎病例的回顾性回顾，苏格兰,在2013年至2018年期间，以及PubMed评论。
结果：普遍出现迹象，建立症状和患者人口统计学数据.此外，定义了与不良结局相关的病例特征.该指南的一个关键特征是定义初始强化治疗的高危患者。评估调查和结果，并适当调整治疗。
结论：这种多部门方法促进了简洁，坏死性外耳道炎管理的系统指南。最初的患者结果似乎很有希望。
