关键词: PEG Polyethylene glycol allergic angioedema

来  源:   DOI:10.5811/cpcem.2020.3.45218   PDF(Sci-hub)   PDF(Pubmed)

Abstract:
UNASSIGNED: We report one of few documented cases of a severe anaphylactic reaction with angioedema to polyethylene glycol (PEG).
UNASSIGNED: The patient presented 30 minutes after onset of his symptoms and quickly developed hypoxia and hypotension refractory to intramuscular epinephrine, intravenous fluids, methylprednisolone, and supplemental oxygen via non-rebreather mask. He ultimately required intubation, an epinephrine infusion, and admission to the medical intensive care unit.
UNASSIGNED: This case depicts a clinical reaction to PEG, a medication rarely implicated in severe anaphylaxis or angioedema.
UNASSIGNED: The allergenic potential of PEG-containing products should be raised, and providers should have a heightened awareness of these potential side effects.
摘要:
我们报告了少数有文献记载的聚乙二醇(PEG)血管性水肿严重过敏反应的病例之一。
患者出现症状30分钟后迅速出现缺氧和低血压,肌内注射肾上腺素难治,静脉输液,甲基强的松龙,和补充氧气通过非呼吸面罩。他最终需要插管,肾上腺素输注,并进入医疗重症监护室。
此病例描述了对PEG的临床反应,很少涉及严重过敏反应或血管性水肿的药物。
应提高含PEG产品的过敏潜力,和提供者应该提高对这些潜在副作用的认识。
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