易洛魁同源异型盒蛋白 2 被确定为帕金森病的潜在生物标志物。
关键词: IRX2 LRRK2 G2019S Parkinson’s disease diagnostic marker intestinal organoid pluripotent stem cells
Mesh : Animals Dopaminergic Neurons / metabolism pathology Homeodomain Proteins / genetics Humans Hypokinesia / diagnosis genetics pathology Intestine, Small / metabolism pathology Leucine-Rich Repeat Serine-Threonine Protein Kinase-2 / genetics Mice Mice, Transgenic Organoids / metabolism Parkinson Disease / diagnosis genetics pathology Pluripotent Stem Cells / metabolism pathology Transcription Factors / genetics Tremor / diagnosis genetics pathology
来 源:
DOI:10.3390/ijms21103455
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