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Abstract：
BACKGROUND: There is an increasing number of reports on the presentation of gastrointestinal symptoms in cases of COVID-19.
OBJECTIVE: To review the studies reporting gastrointestinal symptoms in COVID-19.
RESULTS: Fifteen articles (2,800 patients) were identified. Gastrointestinal symptom frequency varied from 3.0% to 39.6% and included diarrhea (7.5%), náusea (4.5%), anorexia (4.4%), vomiting (1.3%), abdominal pain (0.5%), and belching/reflux (0.3%). Those symptoms can be the first manifestation of COVID-19, but whether they reflect a better or worse prognosis, is controversial. The potential relation of the angiotensin converting enzyme 2 receptor in the digestive tract as an entry route for the virus is discussed.
CONCLUSIONS: Gastrointestinal symptoms may be common in COVID-19, in some cases appearing as the first manifestation, even before fever and respiratory symptoms. Therefore, clinicians and gastroenterologists must be aware of those atypical cases during the current pandemic, as well as of the fecal-oral route and corresponding preventive measures.
OBJECTIVE: To review the studies reporting gastrointestinal symptoms in COVID-19.
RESULTS: Fifteen articles (2,800 patients) were identified. Gastrointestinal symptom frequency varied from 3.0% to 39.6% and included diarrhea (7.5%), náusea (4.5%), anorexia (4.4%), vomiting (1.3%), abdominal pain (0.5%), and belching/reflux (0.3%). Those symptoms can be the first manifestation of COVID-19, but whether they reflect a better or worse prognosis, is controversial. The potential relation of the angiotensin converting enzyme 2 receptor in the digestive tract as an entry route for the virus is discussed.
CONCLUSIONS: Gastrointestinal symptoms may be common in COVID-19, in some cases appearing as the first manifestation, even before fever and respiratory symptoms. Therefore, clinicians and gastroenterologists must be aware of those atypical cases during the current pandemic, as well as of the fecal-oral route and corresponding preventive measures.
摘要：
背景：关于COVID-19病例出现胃肠道症状的报道越来越多。
目的：回顾报告COVID-19胃肠道症状的研究。
结果：确定了15篇文章（2,800名患者）。胃肠道症状频率从3.0％到39.6％不等，包括腹泻（7.5％），恶心（4.5%），厌食症(4.4%),呕吐(1.3%),腹痛（0.5%），和打气/反流(0.3%)。这些症状可能是COVID-19的第一表现，但无论它们反映的是预后更好还是更差，是有争议的。讨论了血管紧张素转换酶2受体在消化道中作为病毒进入途径的潜在关系。
结论：胃肠道症状可能在COVID-19中常见，在某些情况下是首发表现，甚至在发烧和呼吸道症状之前。因此,临床医生和胃肠病学家必须意识到当前大流行期间的非典型病例，以及粪口途径和相应的预防措施。
目的：回顾报告COVID-19胃肠道症状的研究。
结果：确定了15篇文章（2,800名患者）。胃肠道症状频率从3.0％到39.6％不等，包括腹泻（7.5％），恶心（4.5%），厌食症(4.4%),呕吐(1.3%),腹痛（0.5%），和打气/反流(0.3%)。这些症状可能是COVID-19的第一表现，但无论它们反映的是预后更好还是更差，是有争议的。讨论了血管紧张素转换酶2受体在消化道中作为病毒进入途径的潜在关系。
结论：胃肠道症状可能在COVID-19中常见，在某些情况下是首发表现，甚至在发烧和呼吸道症状之前。因此,临床医生和胃肠病学家必须意识到当前大流行期间的非典型病例，以及粪口途径和相应的预防措施。
