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Abstract：
Lobomycosis is a rare granulomatous skin disease with a high prevalence in the Amazon region. The Kaiabi Indians are an especially affected group. We studied the current epidemiologic and clinical progression of lobomycosis among the Kaiabi in Brazil, from initial case reports in 1965 through 2019. A total of 60 lobomycosis cases had been reported among the Kaiabi, and we identified 3 new cases in our review. Of 550 cases of lobomycosis ever reported worldwide, 11.5% were among the Kaiabi. We note a high incidence among female Kaiabi and a precocious onset of disease in this indigenous population. Male Kaiabi frequently are infected with the multicentric form and women more frequently exhibit the localized form. Ulcerated lesions are observed more often in the multicentric form. The prevalence among this indigenous group could be explained by genetic susceptibility and lifestyle, which exposes them to a particular agent in the habitats in which they live.
摘要：
根瘤菌病是一种罕见的肉芽肿性皮肤病，在亚马逊地区患病率很高。Kaiabi印第安人是一个特别受影响的群体。我们研究了巴西Kaiabi中叶真菌病的流行病学和临床进展，从1965年的初始病例报告到2019年。在Kaiabi中共报告了60例叶真菌病病例，我们在审查中发现了3例新病例。在全球报告的550例叶真菌病中，11.5%是凯亚比人。我们注意到女性Kaiabi的发病率很高，并且在该土著居民中早熟。男性Kaiabi经常感染多中心形式，女性更频繁地表现出局部形式。在多中心形式中更经常观察到溃疡病变。这一土著群体的患病率可以用遗传易感性和生活方式来解释，使它们暴露于它们居住的栖息地中的特定媒介。
