关键词: CRISPR screen Clostridium sordellii Paeniclostridium sordellii TcsL bacterial toxin large clostridial toxin semaphorin semaphorin 6,Clostridium difficile
Mesh : A549 Cells Animals Bacterial Proteins Bacterial Toxins / metabolism Binding Sites CRISPR-Cas Systems Cell Line, Tumor Clostridium sordellii / genetics metabolism Clustered Regularly Interspaced Short Palindromic Repeats Endothelial Cells / metabolism Female Gene Knockout Techniques HeLa Cells Humans Lung Neoplasms Male Mice Protein Binding Semaphorins / genetics isolation & purification metabolism Virulence Factors / metabolism
来 源:
DOI:10.1016/j.chom.2020.03.007
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