关键词: Adenocarcinoma Mature teratoma Mediastinum Somatic-type malignancy

Mesh : Adenocarcinoma / diagnostic imaging pathology surgery Cell Transformation, Neoplastic / pathology Chest Tubes Drainage Dyspnea / diagnosis Fluorodeoxyglucose F18 Follow-Up Studies Humans Male Mediastinal Neoplasms / diagnostic imaging pathology surgery Middle Aged Pleural Effusion / diagnosis Positron-Emission Tomography Radiopharmaceuticals Teratoma / diagnostic imaging pathology surgery Thoracotomy

来  源:   DOI:10.1007/s11748-020-01327-0   PDF(Sci-hub)

Abstract:
A 54-year-old male presented with exertional dyspnea, right massive pleural effusion, and an anterior mediastinal tumor (6.5 × 6.2 × 7.6 cm) which continued to grow during the 11-year follow-up period. Fluorodeoxyglucose positron emission tomography demonstrated a focal but remarkable uptake within the tumor mass. After chest tube drainage, the patient underwent surgical resection via a right thoracotomy. The final pathology was determined to be a mature cystic teratoma with malignant transformation to adenocarcinoma. Teratomas with somatic-type malignancy are challenging to diagnose using only preoperative evaluations. Intra-operative findings, histopathological findings, and postoperative management techniques are discussed in this report and emphasize the importance of early resection for treatment of mature teratomas, as well as the recommendation of careful inspection of pathological specimens of long-standing teratomas.
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