关键词: Sarcoidosis lupus pernio non-caseous granulomatous skin involvement

Mesh : Antirheumatic Agents / administration & dosage Biopsy / methods Chilblains / drug therapy etiology pathology Diagnosis, Differential Female Humans Hydroxychloroquine / administration & dosage Inflammation Lung / diagnostic imaging Methylprednisolone / administration & dosage Middle Aged Respiratory Function Tests / methods Sarcoidosis, Pulmonary / diagnosis drug therapy physiopathology Skin / pathology Tomography, X-Ray Computed / methods Treatment Outcome

来  源:   DOI:10.1080/00325481.2020.1733863   PDF(Sci-hub)

Abstract:
Sarcoidosis is a systemic granulomatous disease of unknown cause. Skin involvement may be specific lesions in which granulomas are detected on biopsy or nonspecific lesions without granulomatous inflammation on biopsy. Lupus pernio (LP) occurs in the form of smooth, bright nodules and plaques on the nose, ear, lips, and cheeks. Although presence of skin involvement is frequent, lupus perio is reported as a rare form of extrapulmonary sarcoidosis. A 57-year-old female patient applied to the dermatology outpatient clinic with a lesion on the nose. We report a case of chronic sarcoidosis presenting with lupus pernio with clinical and radiological improvement.
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