Abstract：
Clear cell papillary cystadenoma of the epididymis is an uncommon benign neoplasm, usually seen in patients with von Hippel-Lindau disease. Morphologic and immunohistochemical examination aid in distinguishing clear cell papillary cystadenoma from malignant histologic mimics including low-grade mesothelial proliferations and metastatic clear cell renal cell carcinomas. Analogous lesions have been described in the female genital tract, often posing diagnostic challenges due to their low incidence. Here, we present the difficult diagnostic aspects of the first case of clear cell papillary cystadenoma involving the ovary, including the salient immunohistochemical, ultrastructural, and molecular characteristics.
摘要：
附睾透明细胞乳头状囊腺瘤是一种罕见的良性肿瘤，通常见于vonHippel-Lindau病患者。形态学和免疫组织化学检查有助于区分透明细胞乳头状囊腺瘤与恶性组织学模拟物，包括低度间皮增生和转移性透明细胞肾细胞癌。在女性生殖道中已经描述了类似的病变，由于其发病率低，通常会带来诊断挑战。这里,我们介绍了第一例涉及卵巢的透明细胞乳头状囊腺瘤的困难诊断方面，包括显著的免疫组织化学，超微结构，和分子特征。
