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Abstract：
BACKGROUND: Giant cell reparative granuloma (GCRG) is a rare benign tumor. The jawbone is the most common site of occurrence, followed by sphenoid bone, craniofacial bone, hand and foot bones. The etiology of GCRG is unknown but may be related to an intraosseous hemorrhage following trauma. Despite its benign nature, it could be locally aggressive. To our knowledge, no spinal epidural GCRG case has been reported.
METHODS: A case of man aged 32 years who presented with upper right limb numbness and weakness. Computed tomography showed a round soft tissue mass in the spinal canal at the C7-T1 level. The mass showed isointensity on T1-weighted images, hypointensity on T2-weighted images, and significant enhancement on postcontrast T1-weighted images. The mass localized in the epidural space and was surgically resected. The histologic diagnosis was consistent with GCRG.
CONCLUSIONS: Spinal epidural GCRG is rare and is hardly considered in the differential diagnosis. Preoperative diagnosis of GCRG is challenging, and the definitive diagnosis could only be made by pathological examination. Surgical resection is probably an effective therapy for relief of symptoms.
METHODS: A case of man aged 32 years who presented with upper right limb numbness and weakness. Computed tomography showed a round soft tissue mass in the spinal canal at the C7-T1 level. The mass showed isointensity on T1-weighted images, hypointensity on T2-weighted images, and significant enhancement on postcontrast T1-weighted images. The mass localized in the epidural space and was surgically resected. The histologic diagnosis was consistent with GCRG.
CONCLUSIONS: Spinal epidural GCRG is rare and is hardly considered in the differential diagnosis. Preoperative diagnosis of GCRG is challenging, and the definitive diagnosis could only be made by pathological examination. Surgical resection is probably an effective therapy for relief of symptoms.
摘要：
背景：巨细胞修复性肉芽肿（GCRG）是一种罕见的良性肿瘤。颌骨是最常见的发生部位，其次是蝶骨,颅面骨,手和脚的骨头。GCRG的病因尚不清楚，但可能与创伤后的骨内出血有关。尽管它是良性的，它可能是当地的侵略性。据我们所知,没有脊髓硬膜外GCRG病例的报道。
方法：1例男性，年龄32岁，表现为右上肢麻木无力。计算机断层扫描显示C7-T1水平的椎管内有圆形软组织肿块。质量在T1加权图像上显示等强度，T2加权图像上的低强度，对比后T1加权图像显着增强。肿块位于硬膜外腔，经手术切除。组织学诊断与GCRG一致。
结论：脊髓硬膜外GCRG很少见，在鉴别诊断中几乎不考虑。GCRG的术前诊断具有挑战性，只有通过病理检查才能做出明确的诊断。手术切除可能是缓解症状的有效疗法。
方法：1例男性，年龄32岁，表现为右上肢麻木无力。计算机断层扫描显示C7-T1水平的椎管内有圆形软组织肿块。质量在T1加权图像上显示等强度，T2加权图像上的低强度，对比后T1加权图像显着增强。肿块位于硬膜外腔，经手术切除。组织学诊断与GCRG一致。
结论：脊髓硬膜外GCRG很少见，在鉴别诊断中几乎不考虑。GCRG的术前诊断具有挑战性，只有通过病理检查才能做出明确的诊断。手术切除可能是缓解症状的有效疗法。
