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Abstract：
BACKGROUND: Of all the parts of the larynx, the glottis has the highest frequency of cancer. With disease progression, the vocal cord movement is affected and for advanced stages its anatomical and functional preservation is rarely achievable, if at all.
METHODS: Here we describe a 72-year-old patient who presented with hoarseness for a year and was only able to whisper.
METHODS: A computed tomography (CT) scan of the vocal cords (without contrast) showed higher density tissue. Histological examination disclosed a well-differentiated verrucous squamous cell carcinoma of the glottis.
METHODS: The patient was treated with the oncolytic ECHO-7 virus Rigvir without any of the standard treatments.
RESULTS: As shown by CT scans, the patient has been stabilized, and the laryngeal functions are preserved with the virotherapy still ongoing. The patient was diagnosed over 4.2 years ago.
CONCLUSIONS: Considering the present patient being treated with Rigvir without any standard treatment, the results suggest that Rigvir therapy could be a possible treatment for glottic cancer.
METHODS: Here we describe a 72-year-old patient who presented with hoarseness for a year and was only able to whisper.
METHODS: A computed tomography (CT) scan of the vocal cords (without contrast) showed higher density tissue. Histological examination disclosed a well-differentiated verrucous squamous cell carcinoma of the glottis.
METHODS: The patient was treated with the oncolytic ECHO-7 virus Rigvir without any of the standard treatments.
RESULTS: As shown by CT scans, the patient has been stabilized, and the laryngeal functions are preserved with the virotherapy still ongoing. The patient was diagnosed over 4.2 years ago.
CONCLUSIONS: Considering the present patient being treated with Rigvir without any standard treatment, the results suggest that Rigvir therapy could be a possible treatment for glottic cancer.
摘要：
背景：在喉的所有部分中，声门患癌症的频率最高。随着疾病进展,声带运动受到影响，对于晚期，其解剖和功能保留很少实现，如果有的话。
方法：在这里，我们描述了一位72岁的患者，他出现了一年的声音嘶哑，只能耳语。
方法：声带的计算机断层扫描（CT）扫描（无造影）显示较高密度的组织。组织学检查显示声门的高分化疣状鳞状细胞癌。
方法:患者在没有任何标准治疗的情况下接受溶瘤ECHO-7病毒Rigvir治疗。
结果：如CT扫描所示，病人已经稳定下来,并且喉部功能在病毒治疗仍在进行的情况下得以保留。该患者在4.2年前被诊断出。
结论：考虑到当前患者正在接受Rigvir治疗，没有任何标准治疗，结果表明,Rigvir治疗可能是声门型喉癌的一种可能的治疗方法.
方法：在这里，我们描述了一位72岁的患者，他出现了一年的声音嘶哑，只能耳语。
方法：声带的计算机断层扫描（CT）扫描（无造影）显示较高密度的组织。组织学检查显示声门的高分化疣状鳞状细胞癌。
方法:患者在没有任何标准治疗的情况下接受溶瘤ECHO-7病毒Rigvir治疗。
结果：如CT扫描所示，病人已经稳定下来,并且喉部功能在病毒治疗仍在进行的情况下得以保留。该患者在4.2年前被诊断出。
结论：考虑到当前患者正在接受Rigvir治疗，没有任何标准治疗，结果表明,Rigvir治疗可能是声门型喉癌的一种可能的治疗方法.
