关键词: Carcinoid syndrome Scleroderma Scleroderma-like disorders Sclerodermoid disease Skin

来  源:   DOI:10.1159/000496388   PDF(Sci-hub)   PDF(Pubmed)

Abstract:
Scleroderma is a rare complication of carcinoid syndrome and is usually encountered in the setting of a metastatic primary neuroendocrine tumour of the distal ileum. Associated endocardial fibrosis is a frequent finding and the condition carries a poor prognosis. We report a case of scleroderma occurring in a 72-year-old female with metastatic neuroendocrine carcinoma and associated pericardial fibrosis. The use of an alternative nomenclature such as \"scleroderma-like\" or \"sclerodermoid\" disease is proposed in order to emphasise its distinction from true idiopathic scleroderma, despite the histopathological similarities on skin biopsy.
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