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Abstract：
Parvoviruses in the genera Bocaparvovirus (HBoV), Erythroparvovirus (B19) and Tetraparvovirus (PARV4) are the only autonomous parvoviruses known to be associated with human and non-human primates based on studies and clinical cases in humans worldwide and non-human primates in Asia and Africa. Here, the presence of these agents with pathogenic potential was assessed by PCR in blood and faeces from 55 howler monkeys, 112 white-face monkeys, 3 squirrel monkeys and 127 spider monkeys in Costa Rica and El Salvador. Overall, 3.7% (11/297) of the monkeys had HboV DNA, 0.67% (2/297) had B19 DNA, and 14.1% (42/297) had PARV4 DNA, representing the first detection of these viruses in New World Primates (NWP). Sex was significantly associated with the presence of HBoV, males having greater risk up to nine times compared with females. Captivity was associated with increased prevalence for PARV4 and when all viruses were analysed together. This study provides compelling molecular evidence of parvoviruses in NWPs and underscores the importance of future research aimed at understanding how these viruses behave in natural environments of the Neotropics and what variables may favour their presence and transmission.
摘要：
Bocapavovirus（HBoV）属的细小病毒，根据全球人类和亚洲和非洲的非人类灵长类动物的研究和临床病例，红细胞细小病毒（B19）和四肝病毒（PARV4）是已知与人类和非人类灵长类动物相关的唯一自主细小病毒。这里,通过PCR在55只咆哮猴的血液和粪便中评估了这些具有致病潜力的药物的存在，112只白脸猴子,哥斯达黎加和萨尔瓦多有3只松鼠猴和127只蜘蛛猴。总的来说,3.7％（11/297）的猴子具有HboVDNA，0.67%（2/297）有B19DNA，14.1%(42/297)有PARV4DNA，代表在新世界灵长类动物（NWP）中首次检测到这些病毒。性别与HBoV的存在显著相关，与女性相比，男性的风险高达9倍。当所有病毒一起分析时，圈闭与PARV4的患病率增加相关。这项研究提供了NWP中细小病毒的令人信服的分子证据，并强调了未来研究的重要性，这些研究旨在了解这些病毒在新热带地区的自然环境中的行为方式以及哪些变量可能有利于它们的存在和传播。
