关键词: PLGA nanoparticles STAT3 siRNA chitosan flurbiprofen folic acid
Mesh : Animals Antineoplastic Agents / administration & dosage pharmacokinetics Apoptosis / drug effects genetics Cancer Pain / etiology prevention & control Cell Line, Tumor Cell Survival / drug effects Chitosan / chemistry Cyclooxygenase Inhibitors / administration & dosage pharmacokinetics Drug Carriers / chemistry Flurbiprofen / administration & dosage pharmacokinetics Folic Acid / administration & dosage pharmacokinetics Humans Mice Nanoparticles / chemistry Neoplasms / complications drug therapy pathology Particle Size Polylactic Acid-Polyglycolic Acid Copolymer / chemistry RNA, Small Interfering / administration & dosage genetics STAT3 Transcription Factor / antagonists & inhibitors genetics
来 源:
DOI:10.1080/03639045.2019.1665061
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