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Abstract：
UNASSIGNED: Even though most of the systematic reviews suggest that depression and anxiety are related to poor neonatal outcomes, it is not yet clear whether a dose-response effect exists.
UNASSIGNED: The aim of the present study is to evaluate the amount of depressive and anxiety symptoms in a cohort of pregnant women and its effect on their newborns.
UNASSIGNED: Two hundred ninety-nine women were assessed for anxiety and depressive disorders and anxious and depressive symptoms at near monthly intervals throughout pregnancy. At the time of delivery, we collected the newborns\' gestational age, birth weight and the Apgar score at 1 and 5 min.
UNASSIGNED: Sixty-seven women were diagnosed as depressed and 43 had an anxious disorder. After controlling for confounding variables only the overall levels of anxiety during pregnancy were negatively associated with birth weight (B = -5.76; 95% CI = -10.96, -2.81), suggesting the existence of a \"dose-response\" effect. The birth outcomes in mildly depressed pregnant women were similar to those of nondepressed women.
UNASSIGNED: Anxiety symptoms, beyond a categorical diagnosis, are associated with low birth weight and should be recognized and properly treated during pregnancy.
UNASSIGNED: The aim of the present study is to evaluate the amount of depressive and anxiety symptoms in a cohort of pregnant women and its effect on their newborns.
UNASSIGNED: Two hundred ninety-nine women were assessed for anxiety and depressive disorders and anxious and depressive symptoms at near monthly intervals throughout pregnancy. At the time of delivery, we collected the newborns\' gestational age, birth weight and the Apgar score at 1 and 5 min.
UNASSIGNED: Sixty-seven women were diagnosed as depressed and 43 had an anxious disorder. After controlling for confounding variables only the overall levels of anxiety during pregnancy were negatively associated with birth weight (B = -5.76; 95% CI = -10.96, -2.81), suggesting the existence of a \"dose-response\" effect. The birth outcomes in mildly depressed pregnant women were similar to those of nondepressed women.
UNASSIGNED: Anxiety symptoms, beyond a categorical diagnosis, are associated with low birth weight and should be recognized and properly treated during pregnancy.
摘要：
■尽管大多数系统评价表明抑郁和焦虑与新生儿不良结局有关，目前尚不清楚是否存在剂量效应。
■本研究的目的是评估一组孕妇的抑郁和焦虑症状的数量及其对新生儿的影响。
■在整个怀孕期间，对29名妇女的焦虑和抑郁障碍以及焦虑和抑郁症状进行了评估。在交货时，我们收集了新生儿的胎龄,出生体重和1分钟和5分钟的Apgar评分。
■67名妇女被诊断为抑郁症，43名妇女患有焦虑症。在控制混杂变量后，只有怀孕期间焦虑的总体水平与出生体重呈负相关（B=-5.76；95％CI=-10.96，-2.81），表明存在“剂量-反应”效应。轻度抑郁孕妇的分娩结果与非抑郁妇女相似。
■焦虑症状，除了明确的诊断，与低出生体重有关，应在怀孕期间得到认可和适当治疗。
■本研究的目的是评估一组孕妇的抑郁和焦虑症状的数量及其对新生儿的影响。
■在整个怀孕期间，对29名妇女的焦虑和抑郁障碍以及焦虑和抑郁症状进行了评估。在交货时，我们收集了新生儿的胎龄,出生体重和1分钟和5分钟的Apgar评分。
■67名妇女被诊断为抑郁症，43名妇女患有焦虑症。在控制混杂变量后，只有怀孕期间焦虑的总体水平与出生体重呈负相关（B=-5.76；95％CI=-10.96，-2.81），表明存在“剂量-反应”效应。轻度抑郁孕妇的分娩结果与非抑郁妇女相似。
■焦虑症状，除了明确的诊断，与低出生体重有关，应在怀孕期间得到认可和适当治疗。
